Third generation autologous chondrocyte implantation is a good treatment option for athletic persons

Purpose: Autologous chondrocyte implantation is the established method for the treatment of joint cartilage damage. However, until now has not been established that autologous chondrocyte implantation is the appropriate procedure for the treatment of cartilage defects in the athletics. The purpose of this study was to analyze if the third-generation autologous chondrocyte implantation is an appropriate treatment for people with a disability athletic full cartilage of the knee joint.


Methods: A total of 84 patients were treated with autologous chondrocyte implantation third generation (NOVOCART® 3D). The time the average follow-up was 8 years (5-14). Sports activities measured by the UCLA activity score and Tegner Activity Scale before the onset of knee pain and postoperative in yearly clinical evaluations. 41 athletic and non-athletic 43 (UCLA-Cut-off: 7; Tegner Activity Scale-Cut-off: 4) were analyzed. Patients reported the results captured using a subjective IKDC, Koos, Lysholm score and VAS score on movement.


Results: Patients reported results (IKDC, VAS at rest, in motion VAS) showed a significant improvement (p <0.001) postoperatively. Athletic man showed significantly better results than non-athletic person in the score results were analyzed (IKDC: p <0.01, Koos: p <0.01, Lysholm score: p <0.01). 96.4% of patients can return to sports and more than 50% refundable or exceed their preinjury level of exercise. The remaining patients were downgraded by a median of two points on UCLA- and 2.5 on the Tegner Activity Scale.

The shift from high-impact sports to show active and moderate or mild activity found. In addition, it was shown that preoperative UCLA score and Tegner Activity Scale was significantly correlated with the patients reported postoperative results.


Conclusions: Autologous chondrocyte implantation is a treatment option that is suitable for athletic person with full-thickness cartilage defects in the knee. Back to sports activities is possible, but it includes a shift from high-impact exercise for less strenuous activities.

 Third generation autologous chondrocyte implantation is a good treatment option for athletic persons
Third generation autologous chondrocyte implantation is a good treatment option for athletic persons

Body composition Athletes National Collegiate Athletic Association (NCAA) Division I Women’s Football via Seasons Competitive

The purpose of this study was to examine the body composition of the National Collegiate Athletic Association Division I female soccer player with the position and the season. One hundred and seventy-five female athletes are categorized by the forward position (n = 47), midfielder (n = 51), defender (n = 57), and the keeper (n = 20). A dual X-ray absorptiometry scanning assessed percent body fat, total lean mass, total fat mass, lean mass of the arms and legs and fat mass and visceral adipose tissue. Goalkeeper has a significantly higher number, arm, and leg lean mass and fat mass compared with all other positions (p <0.05).

For seasonal changes, the percentage of body fat was significantly higher in the winter off-season (26.7%) compared with the summer off-season (25.7%) and the pre-season (25.8%; p <0, 01) for all positions. Total and leg lean mass significantly lowered in the winter off-season compared to all the other seasons, and overall lean mass was significantly higher in the summer season of the pre-season (p <0.01).

Gel and PCR Extraction System (100 preps)

9K-006-0007 100preps
EUR 150.05
  • Product category: Molecular Biology Kits/DNA - Extraction/Gel + PCR Extraction

Gel Extraction Kit (200 preps)

9K-006-0002 200preps, 200prep
EUR 348.41
  • Product category: Molecular Biology Kits/DNA - Extraction/Gel Extraction

Gel and PCR Extraction System (200 Preps)

9K-006-0008 200preps, 200prep
EUR 219.65
  • Product category: Molecular Biology Kits/DNA - Extraction/Gel + PCR Extraction

Agarose gel DNA extraction and purification kit

K1441-100
EUR 425.00

Quick Gel Extraction Kit

20-abx098085
  • EUR 286.00
  • EUR 203.00
  • 200 rxns
  • 50 rxns
  • Shipped within 5-10 working days.

PCR Purification Kit (100 preps)

9K-006-0003 100preps
EUR 224.00
  • Product category: Molecular Biology Kits/DNA - Extraction/PCR Products

Plasmid Miniprep Kit (100 preps)

9K-006-0009 100preps
EUR 205.73
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

FastPure Gel DNA Extraction Mini Kit

DC301-01 100 rxn
EUR 129.00

DNA Gel Extraction Kit - 250 Columns

31030-250 1kit
EUR 545.00
Description: Minimum order quantity: 1 unit of 1kit

DNA Gel Extraction Kit - 50 Columns

31030-50 1kit
EUR 155.00
Description: Minimum order quantity: 1 unit of 1kit

LumiPure DNA Gel Extraction Kit, 50

23793 50 preps
EUR 75.00

Protein Extraction Kit from Gel Slices

P519-20 NULL
EUR NULL

Protein Extraction Kit from Gel Slices

P519-80 NULL
EUR NULL

Deoxy+ OneStep RT-PCR Kit, 100 preps

FYT503-100P 1 vial Ask for price

Agarose Gel DNA Extraction and Purification

EP10010 100 Tests
EUR 297.00

EZ-10 Spin Column DNA Gel Extraction Kit

BS353 50Preps
EUR 76.64
  • Product category: Molecular Biology Kits/DNA - Extraction/Gel Extraction

EZ-10 Spin Column DNA Gel Extraction Kit

BS354 100preps
EUR 95.68
  • Product category: Molecular Biology Kits/DNA - Extraction/Gel Extraction

EZ-10 Spin Column DNA Gel Extraction Kit

BS654 250preps
EUR 166.58
  • Product category: Molecular Biology Kits/DNA - Extraction/Gel Extraction

Triton Extraction Buffer(TEB), for Histon Extraction

T8300-100 100ml
EUR 126.00

Deoxy+ TqaMan OneStep qRT-PCRKit wi ROX,100 preps

FYT505-100P 1 vial Ask for price

Xpert Total Histone Extraction Kit

H7200-100 100 ext
EUR 509.00

Silica Gel In Bag, 5G, 100/Pk

DSG111 1PK, 100UNIT
EUR 61.31
  • Product category: Biochemicals/Adsorbents/Drying Agents/Drying Agents

cfPure® Cell Free DNA Extraction Kit, 100 ml

K5011610 1 kit
EUR 448.00

T-Pro Gel/PCR DNA Purification Mini Kit (100)

RB94-NES100 100preps/Kit
EUR 161.00

Plasmid DNA Extraction Mini Kit (100prep)

FAPDE-100 100 preps
EUR 129.00

PCR DNA extraction and purification kit

K1444-100
EUR 338.00

Plasmid DNA extraction and purification kit

K1445-100
EUR 370.00

Viral DNA extraction and purification kit

K1446-100
EUR 479.00

Deoxy+ SYBR Green OneStep qRT-PCRKit wi ROX, 100 preps

FYT504-100P 1 vial Ask for price

cfPure® V2 Cell Free DNA Extraction Kit, 100 ml

K5011610-V2 1 kit
EUR 448.00

FFPE Tissue DNA Extraction Micro kit -- For extraction DNA from paraffin-fixed tissues (100prep)

FAFFM-100 100 preps
EUR 224.00

Blood Genomic DNA Extraction Mini Kit (100prep)

FABGK-100 100 preps
EUR 165.00

Blood genomic DNA extraction and purification kit

K1443-100
EUR 479.00

AIM-100

A3148-100 100 mg
EUR 1859.00
Description: AIM-100 is a small inhibitor of Ack1 tyrosine kinase with IC50 value of 24 nM [1]. AIM-100 mimicked ATP and inhibited the activity of Ack1 significantly and specifically.

LB-100

B4846-100 100 mg
EUR 860.00

EZLys? Bacterial Protein Extraction Reagent

8001-100
EUR 131.00

EZLys? Tissue Protein Extraction Reagent

8002-100
EUR 185.00

EZLys? Yeast Protein Extraction Reagent

8003-100
EUR 185.00

EZLys? Mammalian Protein Extraction Reagent

8004-100
EUR 185.00

Extraction Buffer for 2D Gel with Diluent, 50ml Urea and CHAPS

PL038 50ml
EUR 72.62
  • Product category: Electrophoresis Related/Buffers

Gel-FAST? Gel Staining/Destaining Kit

K901-40
EUR 175.00

SYBR Safe DNA Gel Stain

A8743-100 100x1 ml
EUR 3390.00

Hi-Bind? T-Gel-Agarose

M1313-100
EUR 1501.00

SafePinky DNA Gel Staining Solution

S1000-100 2X500ml
EUR 188.00

Cell & tissue genomic DNA extraction and purification kit

K1442-100
EUR 566.00

Xpert Nuclear Protein Extraction Kit, Nucleic acid free

N2200-100 100 ext Ask for price

PCR Purification Kit (200 preps)

9K-006-0004 200preps, 200prep
EUR 311.00
  • Product category: Molecular Biology Kits/DNA - Extraction/PCR Products

Plasmid Miniprep Kit (200 preps)

9K-006-0010 200preps, 200prep
EUR 273.59
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

Prolysol BC Protein extraction buffer, Bacteria

P4100-100 100 rxns
EUR 226.00

ExoDNA? Extraction Kit

K1242-25
EUR 588.00

ExoDNA? Extraction Kit

K1242-50
EUR 881.00

MTBK_20640-100

AR02-P0011-100 100ug
EUR 1133.00

Etoposide (100 mM)

1043-100
EUR 153.00

S-100 Antibody

3958-100
EUR 316.00

hAlbumin FRET 100

AH1005-100 1 Kit
EUR 212.00

hAlbumin TRF 100

AHTR1005-100 1 Kit
EUR 239.00

hCRP FRET 100

CH1008-100 1 Kit
EUR 212.00

hCRP TRF 100

CHTR1008-100 1 Kit
EUR 239.00

hInsulin FRET 100

IH1010-100 1 Kit
EUR 212.00

hInsulin TRF 100

IHTR1010-100 1 Kit
EUR 239.00

hIgG TRF 100

HITR1011-100 1 Kit
EUR 239.00

rIgG FRET 100

RI1015-100 1 Kit
EUR 212.00

Extraction Buffer for 2D Gel with Diluent, 50ml Urea and NP-40

PL037 50ml
EUR 72.62
  • Product category: Electrophoresis Related/Buffers

Extraction Buffer for 2D Gel with Diluent, 50ml Urea, Thiourea and CHAPS

PL039 50ml
EUR 72.62
  • Product category: Electrophoresis Related/Buffers

SDS-PAGE Resolving Gel Casting Solution

P9050-100 2X500ml
EUR 120.00

Maximo-Gel juice fluorescent Protein-Gel Gel stain

310012 10 ml
EUR 185.00

Maximo-Gel juice fluorescent Protein-Gel Gel stain

310012-L 10x10ml
EUR 1587.00

Gel-Bright LED Gel Illuminator

E90003 1EA
EUR 773.00
Description: Minimum order quantity: 1 unit of 1EA

Finegel SDS-PAGE Running Gel Solution(10%)

F1500-100 2x500ml
EUR 188.00

Finegel SDS-PAGE Running Gel Solution(8%)

F1501-100 2X500ml
EUR 188.00

Finegel SDS-PAGE Running Gel Solution(12.5%)

F1502-100 2X500ml
EUR 188.00

Finegel SDS-PAGE Running Gel Solution(15%)

F1503-100 2X500ml
EUR 188.00

Xpert SDS-PAGE Gel Running Buffer(10X)

P9000-100 1L
EUR 138.00

FUNNEL, 100 MM, PP

6120P-100 12/pk
EUR 47.00
Description: Reusable Plastics; Reusable Funnels

PBS Tablets (100 ml)

2865-100
EUR 164.00

ATP Solution (100 mM)

2121-100
EUR 126.00

CD1b(100-1A5) Antibody

BNC801044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF680 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC041044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF405S conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC051044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF405M conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC401044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF640R conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC681044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF568 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC881044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF488A conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC941044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF594 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC701044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF770 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNCH1044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNCAP1044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNCB1044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), Biotin conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC811044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF680R conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNUB1044-100 100uL
EUR 209.00
Description: Primary antibody against CD1b(100-1A5), Concentration: 0.2mg/mL

CD1b(100-1A5) Antibody

BNC431044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF543 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC471044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF647 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC551044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF555 conjugate, Concentration: 0.1mg/mL

CD1b(100-1A5) Antibody

BNC611044-100 100uL
EUR 199.00
Description: Primary antibody against CD1b(100-1A5), CF660R conjugate, Concentration: 0.1mg/mL

Mouse IgG FRET 100

MIG1012-100 1 Kit
EUR 212.00

Mouse IgM FRET 100

IM1009-100 1 Kit
EUR 212.00

GFP Antibody, 100 uL

P601-100 NULL
EUR NULL

100 BlotBot Reagent Reservoirs

RRVR-100 100pack
EUR 177.00
Description: BlotBot reagent reservoirs will allow dispensing of unique reagents during processing. Pack of 100.

QuantiChrom? LDH Cytotoxicity Assay Kit (C2LD-100)

C2LD-100 100
EUR 127.43
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitative determination of cytotoxicity based on cellular lactate dehydrogenase release into cell culture medium by colorimetric (565nm) method. Procedure: 30 min. Kit size: 100 tests. Detection limit: 2 U/L. Shelf life: 6 months. Shipping: ambient tem

CLOuD9 Gene Expression Regulation Kit (includes 10 ug each of dCas9-PYL1 and dCas9-ABI1 lentivectors, and 100 ul of 0.5M Inducer Agent)

CASCL9-100A-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Rv0351 (GrpE)-100

AR02-P0003-100 100ug
EUR 266.00

Rv1009 (RpfB)-100

AR02-P0006-100 100ug
EUR 1133.00

Rv2450c (RpfE)-100

AR02-P0007-100 100ug
EUR 1133.00

Rv3875 (esxA)-100

AR02-P0008-100 100ug
EUR 1133.00

Rv2031c(HspX)-100

AR02-P0009-100 100ug
EUR 1133.00

Rv3131 (NfnB)-100

AR02-P0010-100 100ug
EUR 1133.00

Biotin TRF 100

BTTR-1006-100 1 Kit
EUR 239.00

Mini gel tubes, 7 x 2.5 x 100 mm, 8/pk

2394132 6unit
EUR 273.00

Bacterial Lipopolysaccharides (LPS) Extraction Kit (up to 50 samples)

1000-100-LPS 1 kit
EUR 408.00

100 bp DNA Ladder (100 bp ~ 1,500 bp, with loading dye)

W0636-100 NULL
EUR NULL

Membrane Protein Extraction Kit

55R-1357 50 assays
EUR 740.00
Description: Membrane Protein Extraction Kit for use in the research laboratory

Mammalian Cell Extraction Kit

55R-1358 500 assays
EUR 381.00
Description: Mammalian Cell Extraction Kit for use in the research laboratory

Up RNA Extraction Kit

20-abx098087
  • EUR 258.00
  • EUR 105.00
  • 100 ml
  • 3 ml
  • Shipped within 5-10 working days.

Plant RNA extraction Kit

20-abx098088
  • EUR 258.00
  • EUR 105.00
  • 100 ml
  • 3 ml
  • Shipped within 5-10 working days.

Total Protein Extraction Kit

BSP003 50Preps
EUR 109.16
  • Product category: Molecular Biology Kits/Protein - Extraction/Animal

Plant Protein Extraction Kit

BSP004 20Preps
EUR 110.90
  • Product category: Molecular Biology Kits/Protein - Extraction/Plant

Nuclear Protein Extraction Kit

BSP009 50Preps
EUR 89.15
  • Product category: Molecular Biology Kits/Protein - Extraction/Animal

FFPE Protein Extraction Kit

BSP058 50Preps
EUR 102.20
  • Product category: Molecular Biology Kits/Protein - Extraction/FFPE Tissue

ChromaFlash Chromatin Extraction Kit

P-2001 100 Extractions
EUR 260.25
Description: The best epigenetics products

Total RNA Extraction Kit

K2014005 1 kit
EUR 344.00
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein Extraction Kit

K2113-50 50 assays
EUR 544.00

Mammalian Cell Extraction Kit

K2114-500 500 assays
EUR 321.00

EpiQuik Nuclear Extraction Kit

OP-0002 100 Assays
EUR 292.15
Description: kits suitable for this type of research

Exosomal RNA Extraction Kit

P200R,-part-of-P200 NULL
EUR NULL

Exosomal DNA Extraction Kit

P230-25 NULL
EUR NULL

Exosomal DNA Extraction Kit

P230-50 NULL
EUR NULL

Genomic DNA Extraction Kit

K5016005 1 kit
EUR 329.00

Plant Tissue Extraction Kit

K296-50
EUR 457.00

Membrane Protein Extraction Kit

K268-50
EUR 539.00

Mammalian Cell Extraction Kit

K269-500
EUR 294.00

Total Protein Extraction Kit

K3011010 1 kit
EUR 370.00
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein Extraction Kit

K3014005 1 kit
EUR 382.00
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Bacterial RNA Extraction Kit

R403-01 100 rxn
EUR 155.00

Tissue RNA Storage Solution (for future RNA extraction)

W0592-100 NULL
EUR NULL

Frit Kit

FRIT-KIT 1each
EUR 124.00
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

SafePinky DNA Gel Staining Solution(10,000X) In Water

S1001-100 1ml
EUR 435.00

Gel Tray

2394250 4unit
EUR 270.00
Description: I ncl udi ng pl at es

Gel Tray

2398194 2unit
EUR 354.00

TC Gel

CP048-005 500 g
EUR 232.00

TC Gel

CP048-010 1 Kg
EUR 347.00

Overall, the goalkeeper significantly different from all other positions. percentage of body fat increases and lean mass decreased in the winter off-season shows an undesirable change of potential in training and / or nutrition during breaks while lean mass was the highest in the summer off-season has the potential to reflect the emphasis on endurance training and increase the volume of training ,